Scientific Articles

The following scientific papers (links) are related to circadian and/or circa-lunar timing cycles and to the role gravitation plays in cell dynamics. They were each published in peer-reviewed journals and are placed here in no hierarchical order. (Some titles have been abbreviated). This list will be updated periodically - if you have an article to suggest, send us the link.

I. Research papers related to CIRCADIAN cycles:

  1. Circadian Metabolism: From Mechanisms to Metabolomics. Cell Press 2016

  2. The Emerging Link Between Cancer, Metabolism and Circadian Rhythms. Nature/Medicine 2018

  3. The Arrival of Circadian Medicine. Nature Reviews/Endochinology 2018

  4. Clocking to Immunity. Nature Reviews/Immunology 2018

  5. Circadian Blueprint of Metabolic Pathways in the Brain. Nature Reviews/Neuroscience 2019

  6. In the Darkness of the Polar Night, Scallops Keep on a Steady Rhythm. Nature/Scientific Reports 2016

  7. Hypophosphatemia Regulates Molecular Mechanism of Circadian Rhythms. Nature/Scientific Reports 2018

  8. Transcriptional Architecture of the Mammalian Circadian Clock. Nature Reviews 2017

  9. Daily Humidity Oscillation Regulates the Circadian Clock to Influence Plant Physiology. Nature/Communications 2017

  10. Spatial and Temporal Chromosomal Organization Driven by Circadian Clock. Nature/Struct. & Molecular Biology. 2013

  11. Light and Circadian Controlled Genes in a Fish. Nature/Scientific Reports 2017

  12. Circadian Rhythms in Mexican Blind Cavefish. Nature/Communications 2013

  13. Effects of Self-Selected Light Cycles and Social Constraints on Sleep and Circadian Timing. Nature/Scientific Reports 2017

  14. Diurnal Variation of Tomato Transcriptome in a Sunlight-Type Plant Factory. Frontiers in Plant Sci. 2016

  15. Entrainment of the Human Circadian System by Light. Journal of Biological Rhythms 2005

  16. The Choroid Plexus is an Important Circadian Component. Nature/Communications 2018

II. Research papers related to CIRCA-LUNAR cycles:

  1. Geonomic Basis of Circadian and Circa-lunar Timing Adaptions in a Midge. Nature/Springer 2016

  2. Circadian and Circatidal Clocks Control the Mechanism of Semilunar Foraging Behavior. Nature/Scientific Reports 2017

  3. Moonlight Controls Lunar-Phase-Dependency in Fish Clock Genes. Nature/Communications 2017

III. Research papers related to metabolism and cell dynamics:

  1. Scaling Functions and Body Size. J. Experimental Biology 2005

  2. Life at Low Reynolds Numbers. E. M. Purcell, Harvard 1976

  3. Primary Cilium as a Gravitational Force Transducer and Regulator of Transcriptional Noise. Developmental Dynamics 2008.

  4. Laws of biology: why so few? Syst. Synth Biol (2010)

  5. Emergence of life: Physical chemistry changes the paradigm. Biology Direct 2015.

IV. Research papers related to gravity, artificial gravity, microgravity and cell order:

  1. Tilted frames and the perception of gravitational vertical and saccadic eye movements. Exp. Brain Res. 2015.

  2. Gravity and neuronal adaptation—from neuronal cells up to neuromuscular responses: a first model. Eur Biophys. J. 2018.

  3. Changes in gravitational force affect gene expression in developing organ systems. BMC Devel. Biology 2005.

  4. Cell Wall Modifications in Response to Gravitational Stress. Plant Physiology 2011.

  5. Incorporation of omics analyses into artificial gravity research for space exploration. Metabolomics 2016.

  6. Effects of microgravity on osteoblast mitochondria: a proteomic and metabolomics profile. Nature/Scientific Reports 2017.

  7. Identification of Reference Genes in Human Myelomonocytic Cells in Altered Gravity. BioMed Res. Int. 2015.

  8. Microarray Study of Arabidopsis thaliana Exposed to Microgravity and Nonmicrogravity. BioMed Res. Int. 2015.

  9. Changes in gravitational field strength affect the state of phosphorylation of stress-related proteins. J. Exp. Botany 2009.

  10. Re-Adaption on Earth after Spaceflights Affects the Mouse Liver Proteome. Int. J. Mol. Sci. 2017.

  11. Transcriptional Homeostasis of Oxidative Stress-Related Pathways in Altered Gravity. Int. J. Mol. Sci. 2018.

  12. Effects of Space Flight on Mouse Liver versus Kidney: Gene Pathway Analyses. Int. J. Mol. Sci. 2018.

  13. Expression of Hypoxia-Inducible Factor and Genes of Related Pathways in Altered Gravity. Int. J. Mol. Sci. 2018.

  14. Leaf movements and their relationship with the lunisolar gravitational force. Annals of Botany. 2015.

  15. Differential Translocation of Nuclear Factor-KappaB Under Gravitational Changes. J. Biomech Eng. 2009.

  16. Muscle Forces or Gravity: What Predominates Mechanical Loading on Bone? Med Sci. Sports Exerc. 2009

  17. Effects of Gravitational Perturbation on Genes Regulating Metabolism in Jurkat Cells. Bol. Med. 2010.

  18. Cell Wall Assembly in Plant Cells Directly Affected by Changes in Gravitational Acceleration. Plos ONE. 2013.

  19. Kinematic Responses to Changes in Walking Orientation and Gravitational Load in Drosophila. Plos ONE. 2014.

  20. Zebrafish Bone and Physiology are Affected by Hormones or Changes in Gravity. Plos ONE. 2015.

  21. New Immune and Disease Related Molecular Signatures During Microgravity Exposure. Nature/Sci.Reports. 2015.

  22. Proposal to Explain Circatidal Rhythm of Arabidopsis thaliana Root Elongation by Lunisolar Gravitation. Ann. Bot. 2017.

  23. Lunar Gravity Affects Leaf Movement of Arabidopsis Thaliana in the International Space Station. Springer-Verlag 2015.

  24. The Botanical Multiverse of Peter Barlow. Communicative and Integrative Biology. 2019.

  25. How Do Ants Make Sense of Gravity? Plos ONE. 2013.

  26. Microtubule Binding Functions in Root Responses to Touch and Gravity Signals. Plant Cell. 2008

  27. Computer Modeling Describes Gravity-Related Adaptation in Cell Cultures. Plos ONE. 2009.

  28. Gravitational Field Enhances Permeability of Biological Membranes to Sucrose. PNAS. 1981.

  29. Control of Adventitious Root Architecture by Darkness, Light, and Gravity. Plant Physiology. 2018.

  30. Gravity-Induced Modifications in Hypocotyls of Arabidopsis Tubulin Mutants. Plant Physiology. 2010.

  31. Modelling the effect of gravity on inert-gas washout outputs. Physiological Reports. 2018.

  32. Pleiotropic effects on the auxin-mediated responses to gravity and light. Plant Signaling and Behavior. 2013.

  33. Cell Mechanosensitivity: Mechanical Properties and Interaction with Gravitational Field. Russian Fed of Biomed. 2012.

  34. Effects of Gravitational Mechanical Unloading in Endothelial Cells. Nature/Sci. Reports. 2013.

  35. Response to Gravity by Zeamays Seedlings. Plant Physiology. 1984.

  36. Potential Gravity-Sensing Role of Vascular Muscle Cell in Altered Gravitational Stimulation. Astrobiology. 2017.

  37. Evolutionary Novelty in Gravity Sensing Through Horizontal Gene Transfer and Protein Assembly. Plus ONE. 2017.

  38. Effects of Gravity Changes on Gene Expression in the Mouse Brain. Plos ONE. 2017.

  39. Hormonal and Gravitropic Specificity in the Regulation of Growth and Cell Wall Synthesis. Plant Physiology. 1995.

  40. Gravity Factor in the Differentiation of Rat Bone Marrow Stem Cells. J. Biomed Sci. 2009.

  41. Oxidative Burst Reaction in Mammalian Cells Depends on Gravity. Cell Communication & Signaling. 2013.

  42. Analyses of a Gravistimulation-Specific Ca2+ Signature using Parabolic Flights. Plant Physiology. 2013.

  43. Arabidopsis LAZY1 Family Plays a Key Role in Gravity Signaling. Plant Cell. 2017.